論文・学術発表

2018年

The administration of high-mobility group box 1 fragment prevents deterioration of cardiac performance by enhancement of bone marrow mesenchymal stem cell homing in the delta-sarcoglycan-deficient hamster.
Kido T, Miyagawa S, Goto T, Tamai K, Ueno T, Toda K, Kuratani T, Sawa Y.
PLoS One. 2018 Dec 5;13(12):e0202838.

2016年

Stem Cell Therapy for Epidermolysis Bullosa-Does It Work?
Tamai K, Uitto J.
J Invest Dermatol. 2016 Nov;136(11):2119-2121.

2015年

Endogenous mesenchymal stromal cells in bone marrow are required to preserve muscle function in mdx mice.
Fujita R, Tamai K, Aikawa E, Nimura K, Ishino S, Kikuchi Y, Kaneda Y.
Stem Cells. 2015 Mar;33(3):962-75.
Transplanted bone marrow-derived circulating PDGFRα+ cells restore type VII collagen in recessive dystrophic epidermolysis bullosa mouse skin graft.
Iinuma S, Aikawa E, Tamai K, Fujita R, Kikuchi Y, Chino T, Kikuta J, McGrath JA, Uitto J, Ishii M, Iizuka H, Kaneda Y.
J Immunol. 2015 Feb 15;194(4):1996-2003.
Systemic high-mobility group box 1 administration suppresses skin inflammation by inducing an accumulation of PDGFRα(+) mesenchymal cells from bone marrow.
Aikawa E, Fujita R, Kikuchi Y, Kaneda Y, Tamai K.
Sci Rep. 2015 Jun 5;5:11008.

2011年

PDGFRalpha-positive cells in bone marrow are mobilized by high mobility group box 1 (HMGB1) to regenerate injured epithelia.
Tamai K, Yamazaki T, Chino T, Ishii M, Otsuru S, Kikuchi Y, Iinuma S, Saga K, Nimura K, Shimbo T, Umegaki N, Katayama I, Miyazaki J, Takeda J, McGrath JA, Uitto J, Kaneda Y.
Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6609-14.

2009年

Molecular therapies for heritable blistering diseases.
Tamai K, Kaneda Y, Uitto J.
Trends Mol Med. 2009 Jul;15(7):285-92.

2008年

Circulating bone marrow-derived osteoblast progenitor cells are recruited to the bone-forming site by the CXCR4/stromal cell-derived factor-1 pathway.
Otsuru S, Tamai K, Yamazaki T, Yoshikawa H, Kaneda Y.
Stem Cells. 2008 Jan;26(1):223-34.
Bone marrow cell transfer into fetal circulation can ameliorate genetic skin diseases by providing fibroblasts to the skin and inducing immune tolerance.
Chino T, Tamai K, Yamazaki T, Otsuru S, Kikuchi Y, Nimura K, Endo M, Nagai M, Uitto J, Kitajima Y, Kaneda Y. Am J Pathol.
2008 Sep;173(3):803-14.

2007年

Bone marrow-derived osteoblast progenitor cells in circulating blood contribute to ectopic bone formation in mice.
Otsuru S, Tamai K, Yamazaki T, Yoshikawa H, Kaneda Y.
Biochem Biophys Res Commun. 2007 Mar 9;354(2):453-8.