Research Paper

2018

The administration of high-mobility group box 1 fragment prevents deterioration of cardiac performance by enhancement of bone marrow mesenchymal stem cell homing in the delta-sarcoglycan-deficient hamster.
Kido T, Miyagawa S, Goto T, Tamai K, Ueno T, Toda K, Kuratani T, Sawa Y.
PLoS One. 2018 Dec 5;13(12):e0202838.

2016

Stem Cell Therapy for Epidermolysis Bullosa-Does It Work?
Tamai K, Uitto J.
J Invest Dermatol. 2016 Nov;136(11):2119-2121.

2015

Endogenous mesenchymal stromal cells in bone marrow are required to preserve muscle function in mdx mice.
Fujita R, Tamai K, Aikawa E, Nimura K, Ishino S, Kikuchi Y, Kaneda Y.
Stem Cells. 2015 Mar;33(3):962-75.
Transplanted bone marrow-derived circulating PDGFRα+ cells restore type VII collagen in recessive dystrophic epidermolysis bullosa mouse skin graft.
Iinuma S, Aikawa E, Tamai K, Fujita R, Kikuchi Y, Chino T, Kikuta J, McGrath JA, Uitto J, Ishii M, Iizuka H, Kaneda Y.
J Immunol. 2015 Feb 15;194(4):1996-2003.
Systemic high-mobility group box 1 administration suppresses skin inflammation by inducing an accumulation of PDGFRα(+) mesenchymal cells from bone marrow.
Aikawa E, Fujita R, Kikuchi Y, Kaneda Y, Tamai K.
Sci Rep. 2015 Jun 5;5:11008.

2011

PDGFRalpha-positive cells in bone marrow are mobilized by high mobility group box 1 (HMGB1) to regenerate injured epithelia.
Tamai K, Yamazaki T, Chino T, Ishii M, Otsuru S, Kikuchi Y, Iinuma S, Saga K, Nimura K, Shimbo T, Umegaki N, Katayama I, Miyazaki J, Takeda J, McGrath JA, Uitto J, Kaneda Y.
Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6609-14.

2009

Molecular therapies for heritable blistering diseases.
Tamai K, Kaneda Y, Uitto J. https://stemrim.com/english/wp/wp-admin/post-new.php?post_type=treatise#edit_timestamp
Trends Mol Med. 2009 Jul;15(7):285-92.