Regeneration-Inducing Medicine™ is a novel mechanism of medicine that “induces the tissue regeneration” just by the administration of a compound, without using any living cells. It activates our body’s innate stem cells to unlock our inherent tissue repair mechanisms to induce the regeneration. This mechanism was discovered by our Scientific Founder, Katsuto Tamai, and research and development for its clinical application have been pursued by StemRIM.

Our body has an innate self-regenerative ability to repair the tissues damaged by injuries or diseases. This ability is attributed to the stem cells capable of differentiating into various cell types. When these stem cells proliferate and differentiate at the damaged tissue, functional tissue regeneration is accelerated.

Regeneration-Inducing Medicine™ increases the supply of the stem cells inside our body. This maximizes our body’s inherent regenerative ability. The concept of StemRIM’s Regeneration-Inducing Medicine™ is to realize tissue regeneration with our own inner stem cells inside our body.

Mechanism of Regeneration-Inducing Medicine™

1. After Regeneration-Inducing Medicine™ is injected into the patient, it circulates through the blood vessel and reaches the bone marrow. There, it activates the mesenchymal stem cells residing in the bone marrow.
2. The activated mesenchymal stem cells leave the bone marrow and travel all over the body through circulation. Then, they accumulate at the damaged tissue.
3. The accumulated mesenchymal stem cells alleviate inflammation and suppress fibrosis (scar formation). Furthermore, they differentiate into proper cell types in response to the local tissue environment, exerting their multipotent differentiation ability. With this mechanism, they regenerate the damaged tissue.